Fluidics Symposium: The Future of Liquid Handling in Point-of-Care Diagnostics

An afternoon programme of talks opening with a keynote address from Yole Développement on the current status and future trends of the point-of-care diagnostics industry, followed by presentations from leading fluid handling and control companies, and concluding with the perspective of a point-of-care diagnostics system developer.



TTP Ventus Fluidics Symposium:
The Future of Liquid Handling in Point-of-Care Diagnostics
9 November 2021 • 13:00-15:20 GMT • Online event • Free to attend


Synopsis

An afternoon programme of talks opening with a keynote address on the current status and future trends of the point-of-care diagnostics industry, followed by technical presentations from two leading fluid handling and control companies, and concluding with the perspective of a point-of-care diagnostics system developer.

Who is this event for?

This event is aimed at engineers, scientists and researchers active in the field of diagnostic systems development, who have a practical, hands-on role in implementing fluid handling and control.
SPEAKERS

Context

The COVID-19 pandemic has fostered a widespread appreciation of the limitations of mainstream infectious disease testing: central lab-based diagnostics may be accurate and sensitive, but sample turn-around times are slow; on the other hand, lateral flow assays are cheap, fast, can be conducted at home, but suffer from lower accuracy and sensitivity. Molecular diagnostics, conducted at the Point-of-Care (POC), addresses these limitations—and with renewed focus on speed and accuracy brought by the pandemic, the market demand for such systems has exploded: the global installed base for POC molecular diagnostic systems increased by 89% during the pandemic; systems are now in use in a broader range of test sites, including pharmacies; and many new players are developing solutions for the market in response to the ever-growing demand in a more-enlightened post-COVID world.

Even the simplest molecular diagnostics workflow will involve a number of steps—lysis, purification, elution, amplification, and detection—requiring flexibility and precision from the liquid handling system. At the same time, POC systems require compact, lightweight components. To meet these requirements, system designers often resort to designing fluidic solutions from the ground up, which carries development cost and risk, and can impact time-to-market. In this symposium, two leading liquid handling companies provide practical approaches and support to help designers to meet these requirements and manage the associated risks. To set the scene, the event will open with a key-note address on the current status and future trends in the point-of-care diagnostics industry, and close with the perspective of a seasoned diagnostics system developer, highlighting the important factors in selecting enabling technologies and partners for solution development.

Programme

Download Programme pdf863.7 kB

Time Title and Synopsis Speaker
13:00 Welcome Tom Harrison
CCO, TTP Ventus
13:05 Key-note address: Microfluidic-based Point-of-Care Testing: market trends and industry landscape

In a world where healthcare is more than ever a priority, micro-technologies are fundamental to building the medical devices that are needed for patient care, diagnostics, and monitoring. Point-of-care / point-of-need testing could be defined as any diagnostic test performed away from reference laboratories, at the “point of need”: at home, at the patient’s bed, in ICUs (Intensive Care Units), at the physician’s office, etc. The overall microfluidic-based point-of-care testing market is expected to grow at a compound annual growth rate (CAGR) 2019-2025 of 13%, primarily driven by diagnostics segments. Moreover, COVID-19 has had a profound impact on the diagnostic ecosystem. Will the pandemic drive the use of point of care testing in new locations, such as the workplace, airports, public transportation, or public places? This talk will present our vision of the point-of-care landscape and new opportunities created.
Jerome Mouly
Team Lead Analyst, Yole Développement
13:50 Controlling fluid volume, position and flow rate with PDF systems

Pressure-Driven Flow (PDF) offers many technical advantages over other pumping mechanisms, and is often the solution of choice when proving principle in the laboratory. However, in order to deploy PDF in diagnostic instrumentation, it is often necessary to carefully control the volume, position and/or flow rate of fluid moved through the system. This talk examines several technical approaches to doing so, providing practical solutions that can be used by system designers.
Stuart Hatfield
R&D Manager, TTP Ventus
14:15 Break
14:25 Flow Control Management Strategies for Point of Care and Point of Use Devices

Microfluidics is paving the way for Point of Care diagnostics: portable, fast and precise instruments which put the capabilities of a medical laboratory in the hands of practitioners at the point of use, such as the operating room. Learn why Fluigent is the ideal partner for compact or benchtop microfluidic instrument design and manufacturing, including proprietary flow control technologies and integration capabilities.
Jacques Pechdimaljian
Product Manager - Industrial Segment, Fluigent
14:50 Standing on the Shoulders of Giants: using established engineering to enable development of novel diagnositics systems

Cutting edge of Point-of-Care Diagnostics systems often attract substantial investment off the back clever solutions to particular problems. However, whilst such solutions may be necessary for drawing investment, it is often the detailed system integration that dictates repeatability/reliability, and as such this can have a significant impact on development cost and time-to-market—or indeed whether a product makes it to market at all. Whilst there are many reasons for this, one challenge technologists face is the selection and integration of supporting technologies and the myriad of problems that come with it. Solving these problems might not always be IP-worthy, but it is necessary for the whole system to work reliably enough to satisfy market needs. Tom uses his experience to explore the important factors in selecting enabling technologies and partners for solution development.
Tom Edwards
VP Engineering, LEX Diagnostics
15:15 Wrap up Tom Harrison
CCO, TTP Ventus

For all questions and enquiries regarding the event, please contact events@ttpventus.com.